The melanocyte inducing hormone is also known as Melanotan 2 and is a peptide. The chemical stimulates skin tanning. Apart from tanning, the chemical also promotes male and female libido. The chemical is used for research purposes across the world for sunless tanning solutions. The benefits of tan can be achieved with Melanotan 2 without exposure to UV rays or direct sunlight. It offers sunless tan to test animals ingested with Melanotan 2. It makes the test animals less prone to sun tan despite their exposure to sunlight on a daily basis.
History of Melanotan 2
The peptide was developed at the College of Medicine under the Jurisdiction of the University of Arizona. The melanocyte inducing hormone offers therapeutic tan and reduces the possibility of occurrence of cancer in the skin. The peptide also helps stimulating sexual vigor in male and female. The Melanotan 2 results in the weight loss by reducing fat mass in the body of the test animals. It is similar to the MSH in the amino acid sequence of NH2.
Melanotan 2 falls into the class of peptides and is also called Melanocortins or MCs. The MCs is a multifunctional peptide regulating a host of functions in the organism. Their importance is also seen in the sexual functions of animals. The peptide was further developed in the year 1998 at the University of Arizona. The Melanotan 2 is more effective as a tanning agent without exposure to sunlight. Melanotan 1 and 2 are synthesized from melanocyte stimulating hormone, and it helps in darkening the skin pigments when coming in contact with sunlight.
Melanotan 1 us a linear peptide with 13 amino acids, but Melanotan 2 is a circular version of the peptide and is shortened. The Melanotan imitates the actions of melanocyte stimulating hormone. It is used in darkening the skin pigments. When your skin comes in contact with Ultra violet radiation, it releases melanocytes to protect the skin from taking in excessive radiation. It is a natural defense process against the harmful UV rays. This process leads to skin darkening or skin tan. Melanotan performs this action in the absence of sunlight. The process is safe as the pigments of the skin responds to the stimulating hormone.
Melanogenesis is formed due to the secretion of natural alpha-melanocyte stimulating hormone. It causes skin tanning. Keeping this knowledge in mind, researchers tested this on animals to check if the hormone can cause skin darkening. The researchers were able to find that it worked, but the half-life of the alpha-MSH was too short. Eventually, they decided to come up with a more stable alternative that could be functional.
In quest of this, the researchers under the leadership of Dr. Victor Hruby synthesized lot of molecules to find a peptide that is stable. After a number of testing and trials, they found a safe and 1000 time potent peptide. This was called Melanotan. The studies from the 1980s go to prove its toxic effect. Skin cancer is a major cause of concern, and Melanotan 2 works as a natural mechanism to stimulate tanning without exposure to UV rays.